Please join us for the 2024 Michael Jaharis Symposium, as well as for refreshments in the Hive Annex after the lecture.

"A Molecular Approach to Additive Manufacturing Medical Devices for Use in The Clinic"

ABSTRACT:

The emergence of additive manufacturing has afforded the ability to fabricate intricate, high resolution, and patient-specific polymeric implants. However, the availability of biocompatible resins with tunable resorption profiles remains a significant hurdle to clinical translation. In this presentation, I will outline our strategies for synthesizing highly functional oligomeric resins that can be photochemically printed into a variety of structures possessing unique mechanical, chemical and degradation properties. I will also describe their use in a number of pre-clinical applications.

BIO:

Matthew L. Becker is the Hugo L. Blomquist Distinguished Professor of Chemistry, Mechanical Engineering & Material Science, Biomedical Engineering and Orthopaedic Surgery at Duke University. His multidisciplinary research team is focused on developing bioactive polymers which address unmet medical needs at the interface of chemistry, materials and medicine. He is a Kavli Fellow and a Fellow of the National Academy of Inventors, the Royal Society of Chemistry, the American Institute of Medical and Biomedical Engineering and the American Chemical Society. From 2009-2019 he was the W. Gerald Austen Endowed Chair of Polymer Science and Engineering at The University of Akron. He earned a Ph.D. in organic chemistry from Washington University in St. Louis (2003) as an NIH Chemistry Biology Interface Training Fellow. From 2003-2005, he was a NRC Postdoctoral Fellow in the Polymers Division of the National Institute of Standards and Technology and remained on the permanent staff until 2009 as a project leader for bioimaging and tissue engineering.

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Mechanisms and Applications of DNA Methylation and Gene Silencing in Plants

DNA methylation is associated with transcriptional repression of eukaryotic genes and transposons. Plants have evolved elaborate systems for the establishment and maintenance of DNA methylation, involving a number of self-reinforcing loop systems that allow for the heritability of DNA methylation difference through mitosis and meiosis. Our lab is studying the components and mechanisms by which DNA methylation is read and interpreted, and how it causes gene silencing or in some cases gene activation. We are developing CRISPR based tools for the precise targeting of DNA methylation changes which can be used in basic plant research or in crop improvement projects.

Steve Jacobsen is an Investigator of the Howard Hughes Medical Institute, and Professor of Molecular Cell and Developmental Biology at the University of California, Los Angeles. His research interests center on mechanisms of epigenetic inheritance in plants, including the genetics and genomics of DNA methylation, histone methylation, and small RNA driven silencing pathways. The lab also develops tools for gene editing in plants, as well as tools for targeted epigenetics using CRISPR systems. He has published over 220 research articles and reviews. Jacobsen received the Beckman and Searle young investigator awards and was elected to the National Academy of Sciences in 2011 and the American Academy of Sciences in 2016.

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McCormick School of Engineering PhD Hooding and Master’s Degree Recognition Ceremony

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McCormick School of Engineering Undergraduate Convocation

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Innovation in Quantum Pedagogy, Application, and its Relation to Culture (IQ-PARC), funded by the Department of Defense — National Defense Education Program, is extending an invitation to underrepresented students nationwide (including military-connected students) to participate in a summer school focused on quantum technologies, to be held at Northwestern University. Join us for presentations by faculty and industry partners introducing quantum technologies, cutting-edge research areas, and related job opportunities particularly in the areas of national security.

This effort aims to foster an inclusive environment that encourages participation from all corners of the academic community. Successful applicants will receive up to $1,000 USD to cover travel and lodging expenses in Evanston, IL.

Priority application deadline: May 15, 2024.

Decisions will be sent by June 15, 2024.

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Register Now

Innovation in Quantum Pedagogy, Application, and its Relation to Culture (IQ-PARC), funded by the Department of Defense — National Defense Education Program, is extending an invitation to underrepresented students nationwide (including military-connected students) to participate in a summer school focused on quantum technologies, to be held at Northwestern University. Join us for presentations by faculty and industry partners introducing quantum technologies, cutting-edge research areas, and related job opportunities particularly in the areas of national security.

This effort aims to foster an inclusive environment that encourages participation from all corners of the academic community. Successful applicants will receive up to $1,000 USD to cover travel and lodging expenses in Evanston, IL.

Priority application deadline: May 15, 2024.

Decisions will be sent by June 15, 2024.

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Register Now